The weight loss landscape in Canada is changing rapidly, and in 2025, two injectable medications—Ozempic and Wegovy—have taken center stage. Originally developed to manage type 2 diabetes, both drugs are now approved for weight loss in non-diabetic individuals and are widely available through Canadian clinics and pharmacies. But which one is better? And what should Canadians know before choosing between the two?
This detailed guide will help you understand how Ozempic vs Wegovy compare in terms of results, cost, side effects, and availability in Canada in 2025.
What Are Ozempic and Wegovy?
Both Ozempic and Wegovy contain semaglutide, a GLP-1 receptor agonist that mimics a hormone involved in appetite regulation. By making you feel fuller for longer, these drugs can significantly reduce calorie intake and support sustainable weight loss.
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Ozempic: Initially designed for diabetes, often prescribed “off-label” for weight loss.
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Wegovy: Contains a higher dose of semaglutide, specifically approved for weight management.
In Canada, both are available by prescription and gaining popularity in non-diabetic patients seeking medically supervised weight reduction.
Ozempic vs Wegovy: Weight Loss Results in 2025
Clinical studies show:
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Wegovy users lose an average of 15% of body weight over 68 weeks.
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Ozempic users lose slightly less—around 10%–12% over the same period.
Wegovy’s higher dosage of semaglutide (2.4 mg vs Ozempic’s 1 mg) is a key factor in its superior fat loss results. However, results also depend on diet, lifestyle changes, and consistent use.
Availability in Canada (2025 Update)
As of mid-2025:
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Wegovy is now fully approved and stocked in most Canadian provinces, after previous shortages in 2024.
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Ozempic remains widely prescribed but may be harder to access for non-diabetic users due to priority given to diabetic patients.
Some provinces are tightening regulations on off-label Ozempic use, especially due to concerns over supply for diabetic patients.
Cost Comparison: Which Is More Affordable?
Without insurance:
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Ozempic: ~$250–$300/month
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Wegovy: ~$350–$400/month
Insurance coverage varies:
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Some private insurance plans cover Wegovy for obesity or BMI-related conditions.
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Public coverage (provincial drug plans) is limited but may expand as obesity is increasingly recognized as a medical issue.
Ask your doctor or pharmacist about prior authorization or health spending accounts to help offset costs.
Side Effects: What to Expect
Both Ozempic and Wegovy can cause side effects—most are digestive in nature:
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Nausea
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Constipation or diarrhea
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Headache
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Fatigue
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Heartburn
Most side effects subside after the first few weeks. Starting on a low dose and increasing gradually can help reduce discomfort. Always use under medical supervision.
Key Differences Between Ozempic and Wegovy in 2025
| Feature | Ozempic | Wegovy |
|---|---|---|
| Approved Use in Canada | Type 2 diabetes | Weight loss (obesity) |
| Typical Dose | 0.25–1.0 mg/week | Up to 2.4 mg/week |
| Avg. Weight Loss | 10%–12% | 15%+ |
| Availability | High, limited for non-diabetics | Full availability for weight loss |
| Cost (without insurance) | $250–$300/month | $350–$400/month |
Who Should Choose Which?
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Choose Ozempic if you:
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Are diabetic or pre-diabetic
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Want a slightly more affordable option
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Have access via insurance or a health plan
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Choose Wegovy if you:
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Are overweight or obese and not diabetic
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Want maximum weight loss results
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Can handle the higher price for better outcomes
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FAQs
Is Wegovy approved for weight loss in Canada?
Yes, as of 2025, Wegovy is fully approved by Health Canada for weight loss in individuals with a high BMI or obesity-related conditions.
Can I use Ozempic for weight loss if I’m not diabetic?
Technically yes—Ozempic is often prescribed “off-label” for weight loss, but many Canadian doctors now prefer prescribing Wegovy due to clearer approval for non-diabetic use.
Which medication causes fewer side effects?
Both have similar side effects, but Wegovy’s higher dosage may increase nausea in some users. Titration (slow dose increase) helps reduce risks.
Will insurance cover Ozempic or Wegovy for weight loss?
Some private insurance plans do, but public coverage is limited. Coverage is more likely for Wegovy in patients with a documented obesity diagnosis.
Do I need to follow a diet or workout plan while using these medications?
Yes—these drugs work best when combined with a calorie-restricted diet and regular exercise. They help curb appetite, but healthy habits are still key.
Conclusion
Both Ozempic and Wegovy have revolutionized weight loss in Canada in 2025, offering new hope for those struggling with obesity. While Wegovy leads in terms of weight loss outcomes, Ozempic remains a solid option—especially for diabetics or budget-conscious users. Before starting either, speak with a healthcare provider to assess your goals, health status, and insurance options.
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